Humatch
Humanness scoring and humanisation guidance for antibody sequences.
OPIG, University of Oxford
What it does
Humanness scoring and humanisation. Input: heavy/light antibody sequences; output: a humanness score per chain plus suggested germline-directed mutations, so you can de-risk a non-human design before ordering it.
Commercial use
Commercial use OKLicence as writtenBSD 3-Clause License
BSD 3-Clause LICENSE file on the repo's master branch; permissive.
The licence read at the source allows use by a company. Attribution or copyleft conditions may still apply — read the note.
Is commercial use free of charge?
Free for commercial useNothing to pay: the licence read at the source grants commercial use with no fee, and the code and weights are public downloads. You still pay for your own compute.
Price and rights are separate: this panel is about money, the panel above is about permission.
When to use it
Use to check how human-like a designed or murine-derived sequence looks before humanisation work. Humanness scores correlate with, but do not measure, clinical immunogenicity.
Facts
- Maker
- OPIG, University of Oxford
- Cost for commercial use
- Free for commercial use
- Compute
- CPU
- Open weights
- Yes
- Licence
- BSD 3-Clause License
- Official site / repo
- github.com/oxpig/Humatch
- Paper
- tandfonline.com
- Last verified
Get told when a licence changes
Licences on these tools do change. One short email when a status flips or a tool is added. No other use of your address.