ANARCI

Numbers antibody and TCR sequences (IMGT, Kabat, Chothia).

OPIG, University of Oxford

What it does

Antibody numbering. Input: antibody or TCR sequences (FASTA); output: the same sequences numbered in IMGT/Kabat/Chothia/Martin with germline V/J assignment and CDR boundaries - the preprocessing step almost every antibody tool expects.

Commercial use

Commercial use OK

Licence as writtenBSD 3-Clause style license (LICENCE file, 2019 Deane et al.)

The LICENCE file contains BSD 3-Clause redistribution terms with no field-of-use restriction; GitHub's license detection also reports BSD-3-Clause.

The licence read at the source allows use by a company. Attribution or copyleft conditions may still apply — read the note.

Is commercial use free of charge?

Free for commercial use

Nothing to pay: the licence read at the source grants commercial use with no fee, and the code and weights are public downloads. You still pay for your own compute.

Proof — pages read on 15 Oct 2026
  1. raw.githubusercontent.com/oxpig/ANARCI/master/LICENCE

Price and rights are separate: this panel is about money, the panel above is about permission.

When to use it

The basic plumbing for any antibody pipeline: numbering, CDR definition, species assignment. Depends on HMMER germline HMMs and can fail on heavily engineered or truncated sequences.

Facts

Maker
OPIG, University of Oxford
Cost for commercial use
Free for commercial use
Compute
CPU
Open weights
Yes
Licence
BSD 3-Clause style license (LICENCE file, 2019 Deane et al.)
Official site / repo
github.com/oxpig/ANARCI
Last verified