by Seq2Study

AbLang2

Antibody-specific language model for paired heavy/light sequences.

OPIG, University of Oxford

What it does

Antibody-specific language model. Input: a paired heavy+light (or single-chain) antibody sequence; output: embeddings and residue likelihoods used to score naturalness, restore missing residues and rank humanisation or affinity-maturation edits.

Commercial use

Commercial use OK

Licence as writtenBSD 3-Clause License

BSD 3-Clause LICENSE file in the repo; permissive, attribution and no-endorsement conditions only.

Proof — pages read on 15 Oct 2026
  1. raw.githubusercontent.com/oxpig/AbLang2/main/LICENSE

The licence read at the source allows use by a company. Attribution or copyleft conditions may still apply — read the note.

Is commercial use free of charge?

Free for commercial use

Nothing to pay: the licence read at the source grants commercial use with no fee, and the code and weights are public downloads. You still pay for your own compute.

Proof — pages read on 15 Oct 2026
  1. raw.githubusercontent.com/oxpig/AbLang2/main/LICENSE

Price and rights are separate: this panel is about money, the panel above is about permission.

When to use it

Use for antibody-aware likelihoods, germline-ness scoring and restoring missing residues in repertoire data. Trained on natural repertoires, so it penalises unusual-but-valid designed CDRs.

Facts

Maker
OPIG, University of Oxford
Cost for commercial use
Free for commercial use
Compute
Single GPU
Open weights
Yes
Licence
BSD 3-Clause License
Official site / repo
github.com/oxpig/AbLang2
Last verified

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