IgLM

Antibody-specific generative language model - academic licence only.

Gray Lab, Johns Hopkins University

What it does

Generates and infills antibody sequences conditioned on species and chain type. Input: a partial antibody sequence with a span to fill, plus species/chain tokens; output: completed sequences with likelihoods, used for library generation and for scoring how natural a designed CDR looks.

Commercial use

Not for commercial use

Licence as writtenJHU Academic Software License Agreement

LICENSE.md is the JHU Academic Software License Agreement, effective only between JHU and 'a non-profit academic or non-profit research institution'. Same pattern as IgFold from the same lab. A company needs a separate agreement with JHU.

Proof — pages read on 15 Oct 2026
  1. raw.githubusercontent.com/Graylab/IgLM/main/LICENSE.md

The licence limits use to non-commercial purposes; a company needs a separate agreement.

Is commercial use free of charge?

No commercial option at any price

No fee for academics; no published commercial price. Commercial use would require negotiating with JHU's technology transfer office.

Proof — pages read on 15 Oct 2026
  1. raw.githubusercontent.com/Graylab/IgLM/main/LICENSE.md

Price and rights are separate: this panel is about money, the panel above is about permission.

When to use it

Academic antibody library generation and naturalness scoring. For commercial work, AbLang2 (BSD-3) and IgBert/IgT5 (MIT) cover the same ground.

Facts

Maker
Gray Lab, Johns Hopkins University
Cost for commercial use
No commercial option at any price
Compute
Single GPU
Open weights
Yes
Licence
JHU Academic Software License Agreement
Official site / repo
github.com/Graylab/IgLM
Last verified