by Seq2Study

La-Proteina

Partially latent flow-matching model generating sequence and all-atom structure jointly.

NVIDIA (BioNeMo)

What it does

Generates a protein's sequence and full all-atom structure (backbone plus side chains) in one pass, including atomistic motif scaffolding. Input: length, or a motif with its atom coordinates; output: all-atom designs that do not need a separate inverse-folding step to get a sequence.

Commercial use

Commercial use OK

Licence as writtenApache License 2.0 (code); NVIDIA Open Model License Agreement (weights); separate dataset licence

This repo splits its licences into a LICENSE/ directory: license_code.txt is Apache-2.0, license_weights.txt is the NVIDIA Open Model License Agreement, and license_datasets.txt covers the data. The Open Model License is the permissive one NVIDIA uses to allow commercial use of model outputs and derivatives, in contrast to the plain 'NVIDIA License' on Proteina which is non-commercial - read the conditions (attribution, trustworthy-AI and no-reverse-engineering terms) before shipping.

The licence read at the source allows use by a company. Attribution or copyleft conditions may still apply — read the note.

Is commercial use free of charge?

Free for commercial use

No fee. Code Apache-2.0 and weights under the NVIDIA Open Model License, which grants use without payment subject to its conditions.

Price and rights are separate: this panel is about money, the panel above is about permission.

When to use it

Attractive when you want sequence and side chains out of the generator itself, especially for atomistic motif scaffolding. Check the Open Model License conditions with counsel; they are permissive but not as plain as MIT.

Facts

Maker
NVIDIA (BioNeMo)
Cost for commercial use
Free for commercial use
Compute
Heavy GPU
Open weights
Yes
Licence
Apache License 2.0 (code); NVIDIA Open Model License Agreement (weights); separate dataset licence
Last verified

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