PepMLM
Masked-language-model generation of linear peptide binders from target sequence alone.
Chatterjee Lab (Duke / Programmable Biology)
What it does
Generates peptide binders without any structure. Input: the target protein sequence and the desired binder length; output: candidate peptide sequences, produced by masked-token generation conditioned on the target - cheap enough to run on a laptop-class GPU.
Commercial use
Not for commercial useLicence as writtenModel card declares MIT, but access is gated behind terms that require non-commercial use
A genuine contradiction, read on the date shown: the Hugging Face card for ChatterjeeLab/PepMLM-650M declares license: mit, while the same card's gated-access fields make you tick 'I agree to use this model for non-commercial use ONLY', plus authorship, data-sharing and no-patent conditions. The GitHub repo publishes no LICENSE file at all. Those access terms are what you actually accept to obtain the weights, so treat it as non-commercial until the authors reconcile the two.
The licence limits use to non-commercial purposes; a company needs a separate agreement.
Is commercial use free of charge?
No commercial option at any priceNo money changes hands, but the access agreement demands non-commercial use and rights concessions, so there is no commercial path. No commercial licence is offered.
Price and rights are separate: this panel is about money, the panel above is about permission.
When to use it
Fast sequence-only peptide binder ideas when you have no structure at all. The access conditions - no patents on generated sequences, authorship on resulting papers - are disqualifying for most company work; read them before downloading.
Facts
- Maker
- Chatterjee Lab (Duke / Programmable Biology)
- Cost for commercial use
- No commercial option at any price
- Compute
- Single GPU
- Open weights
- Yes
- Licence
- Model card declares MIT, but access is gated behind terms that require non-commercial use
- Official site / repo
- github.com/programmablebio/pepmlm
- Paper
- arxiv.org
- Last verified
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